Memantine - What is Memantine, Uses, Side effects, Dosage, Precautions, Interactions, Storage


What is Memantine?

Memantine is a physician recommended medication used to get moderate extreme perplexity (dementia) identified with Alzheimer's infection. It doesn't fix Alzheimer's ailment, however it might improve memory, mindfulness, and the capacity to perform day by day works. This prescription works by obstructing the activity of a specific characteristic substancein the cerebrum (glutamate) that is accepted to be connected to side effects of Alzheimer's malady.

Memantine is accessible under the accompanying diverse brand names: Namenda XR, and Namenda.

Memantine is an oral drug for treating patients with Alzheimer's infection. Different meds utilized for Alzheimer's malady influence acetylcholine, one of the synapse synthetic compounds that nerve cells in the mind use to speak with each other.

Memantine's belongings are free of acetylcholine and acetylcholinesterase. Glutamate is the fundamental excitatory synapse in the mind. It is trusted that an excess of incitement of nerve cells by glutamate might be in charge of the degeneration of nerves that happens in some neurological illnesses, for example, Alzheimer's ailment.

Like different synapses, glutamate is delivered and discharged by nerve cells in the cerebrum. The discharged glutamate at that point goes to close-by nerve cells where it connects to a receptor on the outside of the phones called the N-methyl-D-aspartate (NMDA) receptor. Memantine obstructs this receptor and along these lines diminishes the impacts of glutamate. It is imagined that by hindering the NMDA receptor and the impacts of glutamate, memantine may shield nerve cells from overabundance incitement by glutamate.

Memantine was affirmed by the FDA in October 2003.
Memantine Tablet
Memantine Tablet


Memantine is utilized to get moderate extreme disarray (dementia) identified with Alzheimer's infection. It doesn't fix Alzheimer's infection, yet it might improve memory, mindfulness, and the capacity to perform day by day works. This medicine works by obstructing the activity of a specific common substance in the mind (glutamate) that is accepted to be connected to indications of Alzheimer's ailment.

Instructions to utilize Memantine HCL

Peruse the Patient Information Leaflet if accessible from your drug specialist before you begin taking memantine and each time you get a refill.

Take this prescription by mouth with or without nourishment as coordinated by your specialist. When you first begin taking this medicine, you will generally take it once every day. To diminish your danger of reactions, your specialist may guide you to begin this prescription at a low portion and bit by bit increment your portion. Adhere to your specialist's directions cautiously. When your portion increments to in excess of 5 milligrams for every day, take this medicine twice day by day or as coordinated by your specialist.

On the off chance that you are taking memantine oral fluid, read the maker's guidance sheet that accompanies the container. Pursue the bearings precisely. Utilize the oral syringe that accompanies the item to apportion your portion.  Swallow the medicine legitimately from the syringe. Try not to blend it with water or different fluids. Flush the syringe with water after each utilization. Counsel your specialist or drug specialist on the off chance that you have any inquiries.

Side effects

Body hurts, discombobulation, stoppage, and cerebral pain may happen. On the off chance that any of these impacts endure or intensify, tell your specialist or drug specialist quickly.

Keep in mind that your specialist has recommended this medicine since the person has made a decision about that the advantage to you is more noteworthy than the danger of symptoms. Numerous individuals utilizing this prescription donot have genuine symptoms.

An intense unfavorably susceptible response to this medication is uncommon.

The most well-known symptoms of memantine are:



Increases in pulse





Back torment


Sleepiness (lethargy)



Difficulty relaxing

Memantine may cause a genuine skin response called Stevens-Johnson disorder.

Other potential genuine symptoms include:

Acute renal disappointment

Cerebral dead tissue

Cerebrovascular mishap

Deep venous thrombosis

Hepatitis, liver disappointment

Intracranial discharge

Neuroleptic dangerous disorder


Transient ischemic assault (TIA, smaller than normal stroke)


The normal beginning portion of memantine tablets is 5 mg once day by day.

The portion more often than not is expanded to 5 mg twice day by day, at that point 5 mg and 10 mg as discrete dosages day by day, lastly 10 mg twice every day.

Memantine can be taken with or without sustenance.

The beginning suggested portion of memantine cases is 7 mg every day.

The portion might be expanded week by week by 7 mg every day and the most extreme portion is 28 mg day by day.

Capsules might be gulped down or opened and sprinkled on spoonsful of fruit purée.

Capsules ought not be squashed or bit.


Before taking memantine, tell your specialist or drug specialist on the off chance that you are sensitive to it; or on the off chance that you have some other hypersensitivities. This item may contain dormant fixings which can cause unfavorably susceptible responses or different issues. Converse with your drug specialist for more subtleties.

Prior to utilizing this medicine, tell your specialist or drug specialist your restorative history, particularly of: kidney issues, serious urinary tract contaminations, ongoing dietary change (from a high-protein diet to a vegan diet).

This medication may make you woozy. Try not to drive, use hardware, or do any movement that requires readiness until you are certain you can perform such exercises securely. Point of confinement mixed drinks.

Before having medical procedure, educate your specialist or dental specialist regarding every one of the items you use (counting professionally prescribed medications, nonprescription medications, and natural items).

Amid pregnancy, this prescription ought to be utilized just when unmistakably required. Talk about the dangers and advantages with your specialist.


In the event that your specialist has guided you to utilize this prescription, your specialist or drug specialist may as of now know about any conceivable medication connections and might screen you for them. Try not to begin, stop, or change the dose of any prescription before checking with your specialist, social insurance supplier or drug specialist first.

Memantine has no known extreme cooperations with different medications.

Genuine connections of memantine include:



Moderate connections of memantine include:


aluminum hydroxide



calcium carbonate







sodium bicarbonate

sodium citrate/citrus extract

sodium lactate

tenofovir DF


Mellow Interactions of memantine include:













This data does not contain every single imaginable collaboration or unfriendly impacts. Subsequently, before utilizing this item, tell your specialist or drug specialist of the considerable number of items you use. Keep a rundown of every one of your prescriptions with you, and offer this data with your specialist and drug specialist. Check with your human services proficient or specialist for extra restorative exhortation, or in the event that you have wellbeing questions, concerns or for more data about this drug.


Store at room temperature far from light and dampness. Try not to store in the washroom. Fend off all meds from youngsters and pets.

Try not to flush prescriptions down the latrine or empty them into a channel except if taught to do as such. Appropriately dispose of this item when it is lapsed or never again required.

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